Enrolling
A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee (TRIUMPH-4)
J1I-MC-GZBN - ClinicalTrials.gov - NCT05931367
The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants who have obesity or are overweight and have osteoarthritis of the knee.
Enter your city or zip code to find the nearest site
Trial Summary
Age Range
≥18 yearsConditions the trial is for
Obesity, Overweight and Osteoarthritis of the KneeWhat the trial is testing?
RetatrutideCould I receive a Placebo?
YesEnrollment Goal
405Trial Dates
Aug 1, 2023 - Mar 2026How long will I be in the trial?
The study will last about 77 weeks and may include up to 23 visits.Trial Phase
IIIKey Requirements
Clinical trials have inclusion and exclusion requirements to determine which individuals qualify for participation. Listed below are key requirements for this clinical trial, but there may be additional requirements to qualify.Participants Must:
Have excess weight
Have a history of at least 1 self-reported unsuccessful dietary effort to reduce body weight
Participants Must Not:
Have had a change in body weight greater than 11 pounds within 90 days
Have prior joint replacement in the index knee
Have had injections or other procedures for knee pain within 6 months
Have joint disease in the index knee other than osteoarthritis
Have taken weight loss drugs within 90 days
Have or are planning a surgical treatment for excess weight
Have Type 1 Diabetes, Type 2 Diabetes, or any other type of diabetes
Lilly Trial Alerts
Not the right fit? Sign up to receive updates about new trials that are listed or when a new trial site begins enrolling near you.
Clinical Trial Resources
You will complete the questionnaire on another website.YesNo